Welcome to the Ruan Laboratory

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Cellular metabolism fuels all biological processes, supports tissue and organ homeostasis, and ensures functional adaptations to nutrient availability, damage/injury, infection, etc.  On the other hand, metabolic dysfunction underlies the basis of inflammation, aging, and many diseases including obesity, diabetes, cardiovascular disease, and immune system disorders.  The long-term goal of the Ruan laboratory is to elucidate immunometabolic mechanisms of tissue remodeling, inflammation, and disease susceptibility.  

Keywords: Obesity; Aging; Metabolism; Nutrition & Diets; Inflammation; Immunometabolism; Microbe-host interactions; Stem cells.

We currently conduct an integrated program in three major directions: